Rene Mathis is Bond's ally in Casino Royale, working for MI6. However, it is unclear as to whether or not his loyalty truly lies with Bond. When Bond and treasury officer Vesper Lynd are taken captive by Le Chiffre, Le Chiffre boasts Mathis' loyalty to him. Mathis is accused of sharing Bond's knowledge of Le Chiffre's bluffing twitch with Le Chiffre himself. Bond has MI6 take Mathis into custody under the suspicion of being a traitor. However, when Vesper Lynd is revealed as a traitor, it is questionable as to whether or not Mathis was truly the culprit responsible for sharing Bond's secrets. M claims that the case on Mathis has been cleared, but Bond suspects Mathis could have been working with Lynd and Le Chiffre.

Appears in: Casino Royale, BondQuantum of 22Solace

Portrayed By: Giancarlo Giannini